Acute Kidney Injury during pregnancy

Authors

  • Alexandre Hertig Service de Néphrologie, Hôpital Foch, 40 rue Worth, 92150 Suresnes, France
  • Marie Carbonnel Service de Gynécologie-Obstétrique, Hôpital Foch, 40 rue Worth, 92150 Suresnes, France
  • Charles Cerf Service de Réanimation polyvalente, Hôpital Foch, 40 rue Worth, 92150 Suresnes, France

DOI:

https://doi.org/10.37051/mir-00128

Keywords:

Acute Kidney Injury, Placenta, Pregnancy, Thrombotic microangiopathy

Abstract

In intensive care units, taking care of pregnant women developing acute kidney injury [AKI] pre- or immediately post-partum implies to know the high susceptibility of maternal endothelium. The latter is induced by the presence of a placenta which physiologically produces large amounts of anti-angiogenic factors such as sFlt-1. The main mechanism of AKI is acute tubular necrosis, most probably of ischemic nature. However, when AKI develops contemporarily of a HELLP syndrome (Hemolysis Enzyme Liver Low Platelets),  i.e. of a thrombotic microangiopathy, the differential diagnostic procedure may be highly complex : other causes, exceptional, but calling for more specific therapies than delivery, must indeed be contemplated by the intensivist. In such circumstances, uncover the effect of time alone is key.  

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Published

2022-09-23

How to Cite

Hertig, A., Carbonnel, M., & Cerf, C. (2022). Acute Kidney Injury during pregnancy. Médecine Intensive Réanimation. https://doi.org/10.37051/mir-00128

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