Weaning from renal replacement therapy in the critically ill patient with acute kidney injury

Why ? When ? How ?

Authors

  • Kada Klouche 1. Département de Médecine Intensive Réanimation, CHU Lapeyronie Montpellier. 2. Phymedexp, Université de Montpellier, Inserm, CNRS, CHRU de Montpellier, France. https://orcid.org/0000-0003-1633-7700
  • Vincent Brunot Département de Médecine Intensive Réanimation, CHU Lapeyronie Montpellier.
  • Alexandre Lautrette Médecine Intensive Réanimation, Centre de Lutte Contre le Cancer Jean PERRIN, CHU Clermont-Ferrand. https://orcid.org/0000-0003-4545-7461

DOI:

https://doi.org/10.37051/mir-00086

Keywords:

Acute Kidney Injury, Renal Replacement Therapy (RRT), RRT weaning, urine output, creatinine clearance, urinary urea, urinary creatinine, urinary biomarkers

Abstract

About 10% of ICU patients suffer from acute kidney injury (AKI) requiring renal replacement therapy (RRT) with a mortality rate around 50%. Though most survivors achieve sufficient renal recovery to be weaned from RRT, there are no recognized guidelines data on the optimal period for RRT weaning. Both an unjustified delay and a too early RRT weaning lead to numerous complications. Consequently, RRT weaning must be carried out as early as possible and under the best possible conditions. This review provides the justifications for early RRT weaning, the parameters likely to guide it, and its practical modalities.

Image

Published

2021-09-01

How to Cite

Klouche, K., Brunot, V., & Lautrette, A. (2021). Weaning from renal replacement therapy in the critically ill patient with acute kidney injury: Why ? When ? How ?. Médecine Intensive Réanimation. https://doi.org/10.37051/mir-00086

Issue

Section

Expert Opinion