Sodium bicarbonate for metabolic acidosis

Authors

  • Boris Jung 1. Département de Médecine Intensive Réanimation, CNRS INSERM PhyMedExp, Université de Montpellier. 2. CHU de Montpellier, 34000 Montpellier, France
  • Kada Klouche 1. Département de Médecine Intensive Réanimation, CNRS INSERM PhyMedExp, Université de Montpellier. 2. CHU de Montpellier, 34000 Montpellier, France
  • Samir Jaber 1. Département d’Anesthésie et de Réanimation Saint Eloi, CNRS INSERM PhyMedExp, Université de Montpellier. 2. CHU de Montpellier, 34000 Montpellier, France
  • Naike Bigé Service de Médecine Intensive–Réanimation, hôpital Saint-Antoine, Assistance publique–Hôpitaux de Paris, 184, rue du Faubourg-Saint-Antoine, F-75571 Paris cedex 12, Paris, France

DOI:

https://doi.org/10.37051/mir-00041

Keywords:

Metabolic Acidosis, Acidemia, Sodium Bicarbonate, Renal Replacement Therapy

Abstract

Severe metabolic acidemia is associated with poor prognosis. Possible indications of buffering therapy using sodium bicarbonate infusion depend both of the severity of the patient, the plasma pH and the cause of the acidosis. To better apprehend the balance between the risk and the benefit of administering intravenous sodium bicarbonate, one may take into account both the severity of the acidemia (with a threshold of 7.20) and the presence of an acute kidney injury (a moderate to severe acute kidney injury being in favor of administering intravenous sodium bicarbonate). In this review, we discuss the different indications of using intravenous sodium bicarbonate in the critically ill population.

Published

2020-12-24

How to Cite

Jung, B., Klouche, K., Jaber, S., & Bigé, N. (2020). Sodium bicarbonate for metabolic acidosis. Médecine Intensive Réanimation. https://doi.org/10.37051/mir-00041

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