DRESS Syndrome Associated with Carbamazepine and Cytomegalovirus Viral Reactivation

Authors

  • W. Sellami Laboratoire de recherche LR12DNO1
  • I. Ben Mrad Laboratoire de recherche LR12DNO1
  • Z. Hajjej Laboratoire de recherche LR12DNO1
  • H. Gharssallah Laboratoire de recherche LR12DNO1
  • I. Labbène Laboratoire de recherche LR12DNO1
  • M. Ferjani Laboratoire de recherche LR12DNO1

DOI:

https://doi.org/10.3166/rea-2018-0007

Keywords:

Bundles, Septic shock, Early goal-directed therapy, Fluid administration, Surviving Sepsis Campaign, Vasopressors

Abstract

Drug-induced hypersensitivity or drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe skin adverse drug reaction induced by a limited number of drugs. DRESS syndrome occurs within 1–8 weeks of the treatment. In this article, we have reported two cases of two patients who developed a DRESS syndrome associated with carbamazepine and cytomegalovirus reactivation. All symptoms have been resolved after drug withdrawal and treatment with corticoids and ganciclovir. Through these two observations and after review of the literature, we have discussed the clinical aspects, pathophysiology, and treatment of the DRESS syndrome in this article.

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Published

2018-02-21

How to Cite

Sellami, W., Ben Mrad, I., Hajjej, Z., Gharssallah, H., Labbène, I., & Ferjani, M. (2018). DRESS Syndrome Associated with Carbamazepine and Cytomegalovirus Viral Reactivation. Médecine Intensive Réanimation, 27(1), 86–90. https://doi.org/10.3166/rea-2018-0007

Issue

Vol. 27 No. 1 (2018): Janvier 2018 / Respiratoire

Section

Commented case report