Management of Status Asthmaticus in Children: a Therapeutic Challenge

Abstract

In children, asthma exacerbations are common but can sometimes be life-threatening. Therefore, they require prompt recognition and management. Initial treatment includes systemic corticosteroids, inhaled beta-agonists and anticholinergics, as well as appropriate oxygen therapy. A child that does not subsequently improve will require intravenous bronchodilators (beta-agonists and magnesium) and possibly non-invasive ventilation. In case of conventional therapy failure, invasive ventilation is sometimes necessary and can be combined with various adjunctive therapies which lack formal evidence proving their efficacy.