DRESS syndrome associated with carbamazepine and cytomegalovirus reactivation

Authors

  • W. Sellami hôpital militaire de Tunis
  • H. Gharssallah hôpital militaire de Tunis
  • N. Hichri hôpital militaire de Tunis
  • S. Thabet hôpital militaire de Tunis
  • I. Labbène hôpital militaire de Tunis
  • M. Dridi hôpital militaire de Tunis
  • M. Ferjani hôpital militaire de Tunis

DOI:

https://doi.org/10.1007/s13546-011-0263-x

Keywords:

Tissue PCO2, Venous PCO2, PCO2 gradients, Cardiovascular failure, Microcirculation

Abstract

Drug-induced hypersensitivity or drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe skin adverse drug reaction induced by a limited number of drugs. DRESS syndrome occurs within 1 to 8 weeks of the treatment. We report a 36-year-old man who presented a DRESS syndrome associated with carbamazepine and cytomegalovirus reactivation. All symptoms resolved after drug withdrawal and treatment with corticoids and ganciclovir. The DRESS syndrome features, pathophysiology, and treatment are discussed based on the available literature.

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Published

2011-04-04

How to Cite

Sellami, W., Gharssallah, H., Hichri, N., Thabet, S., Labbène, I., Dridi, M., & Ferjani, M. (2011). DRESS syndrome associated with carbamazepine and cytomegalovirus reactivation. Médecine Intensive Réanimation, 20(3), 251–254. https://doi.org/10.1007/s13546-011-0263-x

Issue

Vol. 20 No. 3 (2011): Mai 2011

Section

Case Report