Veno-venous extracorporeal support to treat acute respiratory distress syndrome: Rationale and clinical objectives

Authors

  • T. Pham APHP
  • J. -C. Richard hôpitaux universitaires de Genève
  • L. Brochard University of Toronto

DOI:

https://doi.org/10.1007/s13546-014-0872-2

Keywords:

Brain death, Paediatrics, Organ donation, Intensive care unit

Abstract

Extracorporeal circulation techniques can be used for the management of severe respiratory failure complicating the acute respiratory distress syndrome with three objectives: 1) to ensure satisfying oxygenation by bypassing the sick lung using a veno-venous circulation with high blood flows; this technique easily extracorporeal permit CO2 elimination; 2) to ensure partial elimination of CO2 with the aim to protect the lungs from risky mechanical ventilation. Four to five times lower blood flows are sufficient with a veno-venous circulation or pumpless arterio-venous techniques; 3) associated cardiac failure may exceptionally require veno-arterial extracorporeal circulation. Physiological studies and clinical trials are absolutely needed to better delineate the indications of these techniques.

Published

2014-04-01

How to Cite

Pham, T., Richard, J. .-C., & Brochard, L. (2014). Veno-venous extracorporeal support to treat acute respiratory distress syndrome: Rationale and clinical objectives. Médecine Intensive Réanimation, 22(Suppl. 3), 577–583. https://doi.org/10.1007/s13546-014-0872-2