Nosocomial Viral Infections: Myth or Reality?

Authors

  • G. Thomas Réanimation des détresses respiratoires et infections sévères, hôpital Nord, Assistance publique-Hôpitaux de Marseille, Aix-Marseille université
  • S. Hraiech Réanimation des détresses respiratoires et infections sévères, hôpital Nord, Assistance publique-Hôpitaux de Marseille, Aix-Marseille université
  • L. Chiche Service de médecine interne, hôpital Conception, Assistance publique-Hôpitaux de Marseille, Aix-Marseille université
  • L. Papazian Réanimation des détresses respiratoires et infections sévères, hôpital Nord, Assistance publique-Hôpitaux de Marseille, Aix-Marseille université
  • J.-M. Forel Réanimation des détresses respiratoires et infections sévères, hôpital Nord, Assistance publique-Hôpitaux de Marseille, Aix-Marseille université

DOI:

https://doi.org/10.1007/s13546-014-1010-x

Abstract

Prevention and treatment of ventilator-associated bacterial pneumonia resulted in numerous publications and guidelines. Respiratory viral “nosocomial” infections, consisting mainly in the reactivation of viruses from the herpes group, were described in the past two decades in the nonimmunocompromised intensive care unit (ICU) patients. The actual pathogenesis of these infections has often been discussed with the assumption that they were the marker of severity of patients’ illness rather than a real disease. To date, they are still underdiagnosed since rarely investigated in previously immunocompetent ICU patients. Several recent studies and meta-analyses suggested that they represent an independent risk factor for mortality and major morbidity to be considered as one separate disease entity by itself. Our purpose is to review respiratory viral infections occurring in the ICU focusing at the supposed pathophysiological mechanisms, risk factors, prognosis and ongoing studies regarding their management.

Published

2015-01-01

How to Cite

Thomas, G., Hraiech, S., Chiche, L., Papazian, L., & Forel, J.-M. (2015). Nosocomial Viral Infections: Myth or Reality?. Médecine Intensive Réanimation, 24(Suppl. 2), S386-S389. https://doi.org/10.1007/s13546-014-1010-x

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