Management of Biofilm-Related Infections in the Intensive Care Unit: Current Guidelines
DOI:
https://doi.org/10.1007/s13546-016-1182-7Keywords:
Aspiration pneumonitis, Aspiration pneumonia, Alteration of consciousness, Antibiotherapy, PreventionAbstract
Biofilms are surface-associated microbial communities that are involved in numerous infectious diseases. Patients in the intensive care units are at high risk of biofilm-related infections due to the frequent insertion of central venous or urinary catheters and orotracheal tubes. Chronic infections can also involve biofilms, even in the absence of medical device. The aim of this review is to describe the main microbiological characteristics of biofilms and the main epidemiologic data regarding the risk of biofilm-related infections in intensive care unit. Then, based on recent French and international guidelines, we will detail the main aspects of their preventive, diagnostic, and therapeutic management.