Kidney Failure during Sepsis: When and How Should I Begin RRT?

Abstract

The best choice of renal replacement therapy technique remains debated in critically ill patients. There is no evidence that this choice impacts on survival, adverse events or renal recovery. The objectives of renal replacement therapy are the correction of metabolic disturbances, the prevention of uremic syndrome and the management fluid balance. These objectives should fit to patient’s needs. Hemodynamic tolerance must be optimized to reach these objectives. If adequate settings are selected, intermittent hemodialysis can be safely applied even in the most severe septic patients.