Immunocompromised patients with lung infection: assessing host specificities

Authors

  • G. Dumas Service de réanimation médicale, hôpital Saint-Antoine
  • N. Bigé Service de réanimation médicale, hôpital Saint-Antoine
  • V. Lemiale Service de réanimation médicale, hôpital Saint-Louis, AP–HP
  • E. Azoulay Service de réanimation médicale, hôpital Saint-Louis, AP–HP

DOI:

https://doi.org/10.3166/rea-2018-0056

Keywords:

Cardiogenic shock, Heart failure, Circulatory support, ECLS, ECMO

Abstract

The number of patients living with immune deficiency has been dramatically increased. Nevertheless, these patients may experience several life-threatening complications warranting admission to the intensive care unit. Respiratory infection remains the leading cause of admission with high reported mortality rates. One could distinguish primary and secondary immunodeficiency disorders. Secondary immunodeficiency disorders are the most frequent ones with the development of new treatments such as targeted therapies. Various infectious disorders may occur with special attention for opportunistic pathogens and latent infection reactivation. Diagnostic strategy gets leading by immunodeficiency condition, prophylaxis, clinical presentation, and radiologic pattern. This drives choices in empiric treatment and diagnosis tools. Physicians must bear in mind that failure to identify the etiology of pulmonary involvement is associated with higher mortality.

Published

2018-08-29

How to Cite

Dumas, G., Bigé, N., Lemiale, V., & Azoulay, E. (2018). Immunocompromised patients with lung infection: assessing host specificities. Médecine Intensive Réanimation, 27(4), 344–366. https://doi.org/10.3166/rea-2018-0056

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