Pulmonary Hypertension in Sickle Cell Disease: Acute or Chronic Complication?

Abstract

Introduction: During sickle cell disease, pulmonary hypertension is common and worsens prognosis. Its diagnosis in time is mandatory.

Case reports: The first case reported chronic pulmonary hypertension that impacts respiratory function. It was suspected during an acute exacerbation which was then confirmed later. The second case described an acute pulmonary hypertension concomitant with an acute chest syndrome that recovered spontaneously after the acute episode resolution.

Conclusions: Pulmonary hypertension noticed within an acute exacerbation of sickle cell disease can be acute and reversible or chronic and permanent. A delayed exploration of the right cardiac function is necessary to plan appropriate monitoring.