Cardiovascular effects of hydrogen sulfide: a review

Authors

  • J. Boisramé-Helms hôpitaux universitaires de Strasbourg
  • P. Asfar université d’Angers
  • P. Radermacher Universitätsklinikum
  • F. Meziani hôpitaux universitaires de Strasbourg

DOI:

https://doi.org/10.1007/s13546-011-0343-y

Abstract

Hydrogen sulfide (H2S) is a gaseous mediator, which has an important role in pathophysiology. It is a vasodilator gas, taking part in particular in the regulation of blood pressure, in the cardiac response to ischemia/reperfusion injury, and in inflammation. In recent decades, H2S and its donors/inhibitors have therefore been studied with growing interest in intensive care units and tested in various animal models; the roles of H2S are still a matter of debate, as it can be considered either a molecule with potential beneficial effect or deleterious. This review summarizes the different properties of H2S in order to point its potential value in intensive care.

Published

2011-11-28

How to Cite

Boisramé-Helms, J., Asfar, P., Radermacher, P., & Meziani, F. (2011). Cardiovascular effects of hydrogen sulfide: a review. Médecine Intensive Réanimation, 21(Suppl. 2), 467–474. https://doi.org/10.1007/s13546-011-0343-y

Issue

Section

Enseignement Supérieur En Réanimation