Ventilatory support in Covid-19 pneumonia

Authors

  • Alain Mercat Département de Médecine Intensive – Réanimation, Vent’Lab, CHU d’Angers, Université d’Angers, France.
  • Julien Demiselle 1. Hôpitaux Universitaires de Strasbourg, Service de Médecine Intensive-Réanimation, Nouvel Hôpital Civil 1, place de l'Hôpital, F-67091, Strasbourg, Cedex, France. 2. INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine (RNM) FMTS, Strasbourg, France. https://orcid.org/0000-0002-7255-1114
  • François Beloncle Département de Médecine Intensive – Réanimation, Vent’Lab, CHU d’Angers, Université d’Angers, France.

DOI:

https://doi.org/10.37051/mir-00068

Keywords:

Mechanical ventilation, Acute Respiratory Distress Syndrome (ARDS), Covid-19

Abstract

The Covid-19 pandemic led to a major influx of patients suffering from acute hypoxemic respiratory failure, which conducted intensivists to adapt ICU structures and question respiratory support strategies. Available data suggest that pathophysiology of Covid-19 associated - acute respiratory distress syndrome (ARDS) is substantially similar to the pathophysiology of ARDS unrelated to Covid-19. Specific vascular injuries may however be more frequent during Covid-19 and some patients may present a major alteration in hypoxic pulmonary vasoconstriction. To date, ventilatory support strategies of patients with Covid-19 should be in line with guidelines for ARDS unrelated to Covid-19, including in particular a cautious evaluation of positive end-expiratory pressure effects.

Image

Published

2021-03-23

How to Cite

Mercat, A., Demiselle, J., & Beloncle, F. (2021). Ventilatory support in Covid-19 pneumonia. Médecine Intensive Réanimation. https://doi.org/10.37051/mir-00068

Issue

Section

Expert Opinion