Carbapenemase-Producing Enterobacteriaceae in Intensive Care Unit: How to Manage the Risk ?

Abstract

The global widespread of carbapenemase-producing enterobacteriaceae, particularly in the Mediterranean area is a challenging situation that needs to keep us alert. Three principal mechanism of resistance, displaying variable expression, are described here in this article. Identifying patient at risk, improving the quality of our microbiological diagnosis and containing the widespread of the resistance in healthcare facilities are essential to help keeping this problem under control. Improvement of hand hygiene compliance, respect of hygiene precaution procedures, and optimizing antibiotic consumption are more than necessary.