Exploration of Microcirculatory Blood Flow During Septic Shock

Authors

  • G. Hariri Service de réanimation médicale, hôpital Saint-Antoine, Assistance publique–Hôpitaux de Paris (AP–HP)
  • J. Joffre Service de réanimation médicale, hôpital Saint-Antoine, Assistance publique–Hôpitaux de Paris (AP–HP)
  • G. Dumas Université Pierre-et-Marie-Curie–Paris-VI, Sorbonne Universités
  • J.-R. Lavillegrand Université Pierre-et-Marie-Curie–Paris-VI, Sorbonne Universités
  • N. Bigé Service de réanimation médicale, hôpital Saint-Antoine, Assistance publique–Hôpitaux de Paris (AP–HP)
  • J.-L. Baudel Service de réanimation médicale, hôpital Saint-Antoine, Assistance publique–Hôpitaux de Paris (AP–HP)
  • B. Guidet Inserm U1136
  • E. Maury Inserm U1136
  • H. Ait-Oufella Inserm U970, centre de recherche cardiovasculaire de Paris (PARCC)

DOI:

https://doi.org/10.3166/rea-2018-0074

Keywords:

Delirium, ICU, Non-Pharmacological interventions

Abstract

Animal and human studies have documented alterations of microcirculatory blood flow during serious infections, potentially leading to lethal organ damages. Both severity and persistence of microcirculatory disorders are predictive factors for mortality, independently of cardiac output or arterial pressure. Several tools derived from skin analysis have been developed, allowing clinicians to quickly evaluate the peripheral perfusion including the temperature gradient, the capillary refill time, the extent of mottling and the peripheral perfusion index. In this review, we have reported that these bedside non-invasive parameters represent interesting tools for risk stratification in septic patients, being related to organ failure severity and predictive of mortality.

Published

2019-03-01

How to Cite

Hariri, G., Joffre, J., Dumas, G., Lavillegrand, J.-R., Bigé, N., Baudel, J.-L., Guidet, B., Maury, E., & Ait-Oufella, H. (2019). Exploration of Microcirculatory Blood Flow During Septic Shock. Médecine Intensive Réanimation, 28(2), 103–113. https://doi.org/10.3166/rea-2018-0074

Most read articles by the same author(s)

1 2 > >>