Renal after effect in ARDS

Abstract

Acute renal failure (AKI) is one of the most common complications seen in patients in the intensive care unit (ICU). As the prevalence of AKI increases with the severity of the disease and the patient's fragile state, AKI is logically frequently observed in patients with acute respiratory distress syndrome (ARDS). However, the epidemiology of the ARI in patients with ARDS is not yet clearly described and debates persist as to a possible excess incidence of ARI in this population.If acute tubular necrosis, according to recent histological studies carried out during the COVID19 pandemic, seems to be the predominant lesion, other lesions observed on the other components of the nephron are not uncommon. Therefore, AKI could be considered as a multifactorial problem occurring after exposure to hypoxemia, inflammation, renal hypoperfusion and nephrotoxic use.The objective of this article is to provide a review of the pathophysiological pathways identified during AKI from human and fundamental translational studies in animals.